Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol

Abstract Performing functional magnetic resonance imaging (fMRI) scans of children can be a difficult task, as participants tend to move while being scanned. Head motion represents a significant confound in fMRI connectivity analyses. One approach to limit motion has been to use shorter MRI protocol...

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Autores principales:	Corey Horien, Scuddy Fontenelle, Kohrissa Joseph, Nicole Powell, Chaela Nutor, Diogo Fortes, Maureen Butler, Kelly Powell, Deanna Macris, Kangjoo Lee, Abigail S. Greene, James C. McPartland, Fred R. Volkmar, Dustin Scheinost, Katarzyna Chawarska, R. Todd Constable
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/17456881c17f4329826410a4bae7873a
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spelling	oai:doaj.org-article:17456881c17f4329826410a4bae7873a2021-12-02T13:34:09ZLow-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol10.1038/s41598-020-78885-z2045-2322https://doaj.org/article/17456881c17f4329826410a4bae7873a2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78885-zhttps://doaj.org/toc/2045-2322Abstract Performing functional magnetic resonance imaging (fMRI) scans of children can be a difficult task, as participants tend to move while being scanned. Head motion represents a significant confound in fMRI connectivity analyses. One approach to limit motion has been to use shorter MRI protocols, though this reduces the reliability of results. Hence, there is a need to implement methods to achieve high-quality, low-motion data while not sacrificing data quantity. Here we show that by using a mock scan protocol prior to a scan, in conjunction with other in-scan steps (weighted blanket and incentive system), it is possible to achieve low-motion fMRI data in pediatric participants (age range: 7–17 years old) undergoing a 60 min MRI session. We also observe that motion is low during the MRI protocol in a separate replication group of participants, including some with autism spectrum disorder. Collectively, the results indicate it is possible to conduct long scan protocols in difficult-to-scan populations and still achieve high-quality data, thus potentially allowing more reliable fMRI findings.Corey HorienScuddy FontenelleKohrissa JosephNicole PowellChaela NutorDiogo FortesMaureen ButlerKelly PowellDeanna MacrisKangjoo LeeAbigail S. GreeneJames C. McPartlandFred R. VolkmarDustin ScheinostKatarzyna ChawarskaR. Todd ConstableNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Corey Horien Scuddy Fontenelle Kohrissa Joseph Nicole Powell Chaela Nutor Diogo Fortes Maureen Butler Kelly Powell Deanna Macris Kangjoo Lee Abigail S. Greene James C. McPartland Fred R. Volkmar Dustin Scheinost Katarzyna Chawarska R. Todd Constable Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol
description	Abstract Performing functional magnetic resonance imaging (fMRI) scans of children can be a difficult task, as participants tend to move while being scanned. Head motion represents a significant confound in fMRI connectivity analyses. One approach to limit motion has been to use shorter MRI protocols, though this reduces the reliability of results. Hence, there is a need to implement methods to achieve high-quality, low-motion data while not sacrificing data quantity. Here we show that by using a mock scan protocol prior to a scan, in conjunction with other in-scan steps (weighted blanket and incentive system), it is possible to achieve low-motion fMRI data in pediatric participants (age range: 7–17 years old) undergoing a 60 min MRI session. We also observe that motion is low during the MRI protocol in a separate replication group of participants, including some with autism spectrum disorder. Collectively, the results indicate it is possible to conduct long scan protocols in difficult-to-scan populations and still achieve high-quality data, thus potentially allowing more reliable fMRI findings.
format	article
author	Corey Horien Scuddy Fontenelle Kohrissa Joseph Nicole Powell Chaela Nutor Diogo Fortes Maureen Butler Kelly Powell Deanna Macris Kangjoo Lee Abigail S. Greene James C. McPartland Fred R. Volkmar Dustin Scheinost Katarzyna Chawarska R. Todd Constable
author_facet	Corey Horien Scuddy Fontenelle Kohrissa Joseph Nicole Powell Chaela Nutor Diogo Fortes Maureen Butler Kelly Powell Deanna Macris Kangjoo Lee Abigail S. Greene James C. McPartland Fred R. Volkmar Dustin Scheinost Katarzyna Chawarska R. Todd Constable
author_sort	Corey Horien
title	Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol
title_short	Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol
title_full	Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol
title_fullStr	Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol
title_full_unstemmed	Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol
title_sort	low-motion fmri data can be obtained in pediatric participants undergoing a 60-minute scan protocol
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/17456881c17f4329826410a4bae7873a
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Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol

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