Actinobacillus pleuropneumoniae exotoxin ApxI induces cell death via attenuation of FAK through LFA-1

Abstract ApxI exotoxin is an important virulence factor derived from Actinobacillus pleuropneumoniae that causes pleuropneumonia in swine. Here, we investigate the role of lymphocyte function-associated antigen 1 (LFA-1, CD11a/CD18), a member of the β2 integrin family, and the involvement of the int...

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Autores principales: Siou-Cen Li, Yu-Tsen Cheng, Ching-Yang Wang, Jia-Ying Wu, Zeng-Weng Chen, Jyh-Perng Wang, Jiunn-Horng Lin, Shih-Ling Hsuan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/179341b87cb54ba3839993b114444a2d
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