Programmable C:G to G:C genome editing with CRISPR-Cas9-directed base excision repair proteins
Many diseases are caused by single-nucleotide polymorphisms. Here, the authors present CRISPR base editors that use the base excision machinery for single-base transversions.
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Main Authors: | , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/179d414f933d4b028a782187beb2408e |
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