Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution

The spike glycoprotein in coronaviruses is a key viral protein for cross-species transmission and infection. Here, the authors present the cryo-EM structures of the spike ectodomains from bat and pangolin coronaviruses, compare them with the available SARS-CoV-2 spike structures and discuss implicat...

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Autores principales: Shuyuan Zhang, Shuyuan Qiao, Jinfang Yu, Jianwei Zeng, Sisi Shan, Long Tian, Jun Lan, Linqi Zhang, Xinquan Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/17b41dd8bc41443aa37164fef7711732
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spelling oai:doaj.org-article:17b41dd8bc41443aa37164fef77117322021-12-02T13:32:57ZBat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution10.1038/s41467-021-21767-32041-1723https://doaj.org/article/17b41dd8bc41443aa37164fef77117322021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21767-3https://doaj.org/toc/2041-1723The spike glycoprotein in coronaviruses is a key viral protein for cross-species transmission and infection. Here, the authors present the cryo-EM structures of the spike ectodomains from bat and pangolin coronaviruses, compare them with the available SARS-CoV-2 spike structures and discuss implications for the evolution and cross-species transmission of SARS-CoV-2.Shuyuan ZhangShuyuan QiaoJinfang YuJianwei ZengSisi ShanLong TianJun LanLinqi ZhangXinquan WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shuyuan Zhang
Shuyuan Qiao
Jinfang Yu
Jianwei Zeng
Sisi Shan
Long Tian
Jun Lan
Linqi Zhang
Xinquan Wang
Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution
description The spike glycoprotein in coronaviruses is a key viral protein for cross-species transmission and infection. Here, the authors present the cryo-EM structures of the spike ectodomains from bat and pangolin coronaviruses, compare them with the available SARS-CoV-2 spike structures and discuss implications for the evolution and cross-species transmission of SARS-CoV-2.
format article
author Shuyuan Zhang
Shuyuan Qiao
Jinfang Yu
Jianwei Zeng
Sisi Shan
Long Tian
Jun Lan
Linqi Zhang
Xinquan Wang
author_facet Shuyuan Zhang
Shuyuan Qiao
Jinfang Yu
Jianwei Zeng
Sisi Shan
Long Tian
Jun Lan
Linqi Zhang
Xinquan Wang
author_sort Shuyuan Zhang
title Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution
title_short Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution
title_full Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution
title_fullStr Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution
title_full_unstemmed Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution
title_sort bat and pangolin coronavirus spike glycoprotein structures provide insights into sars-cov-2 evolution
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/17b41dd8bc41443aa37164fef7711732
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