Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins provide insights into coronavirus evolution

por Jinfang Yu, Shuyuan Qiao, Runyu Guo, Xinquan Wang
Publicado 2020

Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution

por Shuyuan Zhang, Shuyuan Qiao, Jinfang Yu, Jianwei Zeng, Sisi Shan, Long Tian, Jun Lan, Linqi Zhang, Xinquan Wang
Publicado 2021

Exploiting pH-Regulated Dimer-Tetramer Transformation of Concanavalin A to Develop Colorimetric Biosensing of Bacteria

por Xiahong Xu, Yuwei Yuan, Guixian Hu, Xiangyun Wang, Peipei Qi, Zhiwei Wang, Qiang Wang, Xinquan Wang, Yingchun Fu, Yanbin Li, Hua Yang
Publicado 2017

Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein

por Haixia Zhou, Yingzhu Chen, Shuyuan Zhang, Peihua Niu, Kun Qin, Wenxu Jia, Baoying Huang, Senyan Zhang, Jun Lan, Linqi Zhang, Wenjie Tan, Xinquan Wang
Publicado 2019

BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes

por Zhen Qi, Yehua Li, Bing Zhao, Chi Xu, Yuan Liu, Haonan Li, Bingjie Zhang, Xinquan Wang, Xiao Yang, Wei Xie, Baojie Li, Jing-Dong Jackie Han, Ye-Guang Chen
Publicado 2017

Mutation Y453F in the spike protein of SARS-CoV-2 enhances interaction with the mink ACE2 receptor for host adaption.

por Wenlin Ren, Jun Lan, Xiaohui Ju, Mingli Gong, Quanxin Long, Zihui Zhu, Yanying Yu, Jianping Wu, Jin Zhong, Rong Zhang, Shilong Fan, Guocai Zhong, Ailong Huang, Xinquan Wang, Qiang Ding
Publicado 2021

Mutation Y453F in the spike protein of SARS-CoV-2 enhances interaction with the mink ACE2 receptor for host adaption

por Wenlin Ren, Jun Lan, Xiaohui Ju, Mingli Gong, Quanxin Long, Zihui Zhu, Yanying Yu, Jianping Wu, Jin Zhong, Rong Zhang, Shilong Fan, Guocai Zhong, Ailong Huang, Xinquan Wang, Qiang Ding
Publicado 2021

Erratum: Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection

por Teng Zuo, Jianfeng Sun, Guiqin Wang, Liwei Jiang, Yanan Zuo, Danyang Li, Xuanling Shi, Xi Liu, Shilong Fan, Huanhuan Ren, Hongxing Hu, Lina Sun, Boping Zhou, Mifang Liang, Paul Zhou, Xinquan Wang, Linqi Zhang
Publicado 2016

ULK1 phosphorylates Exo70 to suppress breast cancer metastasis

por Liyuan Mao, Yan-yan Zhan, Bin Wu, Qiang Yu, Liang Xu, Xiaoting Hong, Linhai Zhong, Panying Mi, Li Xiao, Xinquan Wang, Hanwei Cao, Wenqing Zhang, Binbin Chen, Jingzhou Xiang, Kunrong Mei, Ravi Radhakrishnan, Wei Guo, Tianhui Hu
Publicado 2020

A potent and protective human neutralizing antibody targeting a novel vulnerable site of Epstein-Barr virus

por Qian-Ying Zhu, Sisi Shan, Jinfang Yu, Si-Ying Peng, Cong Sun, Yanan Zuo, Lan-Yi Zhong, Shu-Mei Yan, Xiao Zhang, Ziqing Yang, Yong-Jian Peng, Xuanling Shi, Su-Mei Cao, Xinquan Wang, Mu-Sheng Zeng, Linqi Zhang
Publicado 2021

Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry

por Jiwan Ge, Ruoke Wang, Bin Ju, Qi Zhang, Jing Sun, Peng Chen, Senyan Zhang, Yuling Tian, Sisi Shan, Lin Cheng, Bing Zhou, Shuo Song, Juanjuan Zhao, Haiyan Wang, Xuanling Shi, Qiang Ding, Lei Liu, Jincun Zhao, Zheng Zhang, Xinquan Wang, Linqi Zhang
Publicado 2021

Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2

por Qi Zhang, Bin Ju, Jiwan Ge, Jasper Fuk-Woo Chan, Lin Cheng, Ruoke Wang, Weijin Huang, Mengqi Fang, Peng Chen, Bing Zhou, Shuo Song, Sisi Shan, Baohua Yan, Senyan Zhang, Xiangyang Ge, Jiazhen Yu, Juanjuan Zhao, Haiyan Wang, Li Liu, Qining Lv, Lili Fu, Xuanling Shi, Kwok Yung Yuen, Lei Liu, Youchun Wang, Zhiwei Chen, Linqi Zhang, Xinquan Wang, Zheng Zhang
Publicado 2021

Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2

por Shihui Sun, Hongjing Gu, Lei Cao, Qi Chen, Qing Ye, Guan Yang, Rui-Ting Li, Hang Fan, Yong-Qiang Deng, Xiaopeng Song, Yini Qi, Min Li, Jun Lan, Rui Feng, Yan Guo, Na Zhu, Si Qin, Lei Wang, Yi-Fei Zhang, Chao Zhou, Lingna Zhao, Yuehong Chen, Meng Shen, Yujun Cui, Xiao Yang, Xinquan Wang, Wenjie Tan, Hui Wang, Xiangxi Wang, Cheng-Feng Qin
Publicado 2021

Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia

por Xiao-Yan Zhao, Andreas Wilmen, Dongli Wang, Xinquan Wang, Maxine Bauzon, Ji-Yun Kim, Lars Linden, Liang Li, Ursula Egner, Tobias Marquardt, Dieter Moosmayer, Jan Tebbe, Julian Marius Glück, Philipp Ellinger, Kirk McLean, Shujun Yuan, Subramanian Yegneswaran, Xiaoqiao Jiang, Vince Evans, Jian-Ming Gu, Doug Schneider, Ying Zhu, Yifan Xu, Cornell Mallari, Ashley Hesslein, Yan Wang, Nicole Schmidt, Katrin Gutberlet, Christine Ruehl-Fehlert, Alexius Freyberger, Terry Hermiston, Chandra Patel, Derek Sim, Laurent O. Mosnier, Volker Laux
Publicado 2020