Four amino acids within a tandem QxVx repeat in a predicted extended α-helix of the Smad-binding domain of Sip1 are necessary for binding to activated Smad proteins.

por Andrea Conidi, Veronique van den Berghe, Kris Leslie, Agata Stryjewska, Hua Xue, Ye-Guang Chen, Eve Seuntjens, Danny Huylebroeck
Publicado 2013

BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes

por Zhen Qi, Yehua Li, Bing Zhao, Chi Xu, Yuan Liu, Haonan Li, Bingjie Zhang, Xinquan Wang, Xiao Yang, Wei Xie, Baojie Li, Jing-Dong Jackie Han, Ye-Guang Chen
Publicado 2017

Establishment of human distal lung organoids for SARS-CoV-2 infection

por Ting Wang, Ning Zhang, Shipan Fan, Lianzheng Zhao, Wanlu Song, Yuhuan Gong, Quan Shen, Cheng Zhang, Peng Ren, Chutong Lin, Wei Fu, George F. Gao, Shaohua Ma, Yuhai Bi, Ye-Guang Chen
Publicado 2021

Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway

por Dan He, Hongguang Wu, Jinnan Xiang, Xinsen Ruan, Peike Peng, Yuanyuan Ruan, Ye-Guang Chen, Yibin Wang, Qiang Yu, Hongbing Zhang, Samy L. Habib, Ronald A. De Pinho, Huijuan Liu, Baojie Li
Publicado 2020