BRAF mutations may identify a clinically distinct subset of glioblastoma
Abstract Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Prior studies examining the mutational landscape of GBM revealed recurrent alterations in genes that regulate the same growth control pathways. To this regard, ~ 40% of GBM harbor EGFR alterations, whereas BRAF v...
Enregistré dans:
Auteurs principaux: | Samantha N. McNulty, Katherine E. Schwetye, Cole Ferguson, Chad E. Storer, George Ansstas, Albert H. Kim, David H. Gutmann, Joshua B. Rubin, Richard D. Head, Sonika Dahiya |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/17c10ebeab7c45f8a0a11cd5fc0b8d2c |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Clonal selection confers distinct evolutionary trajectories in BRAF-driven cancers
par: Priyanka Gopal, et autres
Publié: (2019) -
Correction: Heterogeneity of subsets in glioblastoma mediated by Smad3 palmitoylation
par: Xiaoqing Fan, et autres
Publié: (2021) -
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
par: Fumitaka Mizoguchi, et autres
Publié: (2018) -
SPECIFICITIES OF THE SUBSET PROFILE OF PERIPHERAL BLOOD IN PATIENTS WITH GLIOBLASTOMA: PATHOGENETIC AND CLINICAL ASSESSMENTS
par: V. A. Chumakov, et autres
Publié: (2014) -
Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency.
par: Megan C Hanna, et autres
Publié: (2013)