The Identification of a Tumor Infiltration CD8+ T-Cell Gene Signature That Can Potentially Improve the Prognosis and Prediction of Immunization Responses in Papillary Renal Cell Carcinoma

The Identification of a Tumor Infiltration CD8+ T-Cell Gene Signature That Can Potentially Improve the Prognosis and Prediction of Immunization Responses in Papillary Renal Cell Carcinoma

BackgroundCD8+ T cells, vital effectors pertaining to adaptive immunity, display close relationships to the immunization responses to kill tumor cells. Understanding the effect exerted by tumor infiltration CD8+ T cells in papillary renal cell carcinoma (papRCC) is critical for assessing the prognos...

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Main Authors: Jie Wang, Meiying Huang, Peng Huang, Jingjie Zhao, Junhua Tan, Feifan Huang, Ruiying Ma, Yu Xiao, Gao Deng, Liuzhi Wei, Qiuju Wei, Zechen Wang, Siyuan He, Jiajia Shen, Suren Sooranna, Lingzhang Meng, Jian Song
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
tumor infiltration immune cells
prognostic model
papillary renal cell carcinoma
CD8+ T cell
scRNA-seq
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/17deac4244264fb9afa61778d01ea6d1
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https://doaj.org/article/17deac4244264fb9afa61778d01ea6d1

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