The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site
Abstract GPR139 is an orphan G protein-coupled receptor expressed in the brain, in particular in the habenula, hypothalamus and striatum. It has therefore been suggested that GPR139 is a possible target for metabolic disorders and Parkinson’s disease. Several surrogate agonist series have been publi...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2017
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/17e7b959f6554066a99116d9312ac208 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|