Novel small RNA spike-in oligonucleotides enable absolute normalization of small RNA-Seq data

Abstract Normalization of high-throughput small RNA sequencing (sRNA-Seq) data is required to compare sRNA levels across different samples. Commonly used relative normalization approaches can cause erroneous conclusions due to fluctuating small RNA populations between tissues. We developed a set of...

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Autores principales: Stefan Lutzmayer, Balaji Enugutti, Michael D. Nodine
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/17fc805a814547d18b623e1269983cae
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