Transglutaminase 2 undergoes a large conformational change upon activation.
Human transglutaminase 2 (TG2), a member of a large family of enzymes that catalyze protein crosslinking, plays an important role in the extracellular matrix biology of many tissues and is implicated in the gluten-induced pathogenesis of celiac sprue. Although vertebrate transglutaminases have been...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2007
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Acceso en línea: | https://doaj.org/article/1807f4db44564b6e8e5268aebe2b45fa |
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