Transglutaminase 2 undergoes a large conformational change upon activation.
Human transglutaminase 2 (TG2), a member of a large family of enzymes that catalyze protein crosslinking, plays an important role in the extracellular matrix biology of many tissues and is implicated in the gluten-induced pathogenesis of celiac sprue. Although vertebrate transglutaminases have been...
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| Main Authors: | , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2007
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| Subjects: | |
| Online Access: | https://doaj.org/article/1807f4db44564b6e8e5268aebe2b45fa |
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