Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance

Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance

The fungal pathogen Candida glabrata readily acquires resistance to multiple types of antifungal drugs. Here, Healey et al. show that C. glabrataclinical isolates often carry mutations in a gene involved in DNA mismatch repair, and this is associated with increased propensity to develop antifungal r...

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Autores principales: Kelley R. Healey, Yanan Zhao, Winder B. Perez, Shawn R. Lockhart, Jack D. Sobel, Dimitrios Farmakiotis, Dimitrios P. Kontoyiannis, Dominique Sanglard, Saad J. Taj-Aldeen, Barbara D. Alexander, Cristina Jimenez-Ortigosa, Erika Shor, David S. Perlin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/1815c031c89a4873a9003da52493606b
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https://doaj.org/article/1815c031c89a4873a9003da52493606b

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