Inhibition of Rho Activity Increases Expression of SaeRS-Dependent Virulence Factor Genes in <named-content content-type="genus-species">Staphylococcus aureus</named-content>, Showing a Link between Transcription Termination, Antibiotic Action, and Virulence

Inhibition of Rho Activity Increases Expression of SaeRS-Dependent Virulence Factor Genes in <named-content content-type="genus-species">Staphylococcus aureus</named-content>, Showing a Link between Transcription Termination, Antibiotic Action, and Virulence

ABSTRACT Staphylococcus aureus causes various diseases ranging from skin and soft tissue infections to life-threatening infections. Adaptation to the different host niches is controlled by a complex network of transcriptional regulators. Global profiling of condition-dependent transcription revealed...

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Bibliographic Details
Main Authors: Anna Nagel, Stephan Michalik, Michel Debarbouille, Tobias Hertlein, Manuela Gesell Salazar, Hermann Rath, Tarek Msadek, Knut Ohlsen, Jan Maarten van Dijl, Uwe Völker, Ulrike Mäder
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
SaeRS TCS
Staphylococcus aureus
antisense transcription
bicyclomycin
proteome
transcription termination
Microbiology
QR1-502
Online Access:https://doaj.org/article/18531e5a96654e92bd4f0c6a1aa8ed30
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