Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma

PD-1 blockade is effective for only a subset of patients with cutaneous T cell lymphomas. Here, the authors report a spatial biomarker that uses immune and cancer cell topography to predict response to PD-1 blockade in this disease.

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Bibliographic Details
Main Authors: Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S. Bhate, Graham L. Barlow, Sizun Jiang, Janos Demeter, Kimberly S. Smythe, Robert H. Pierce, Steven P. Fling, Nirasha Ramchurren, Martin A. Cheever, Yury Goltsev, Robert B. West, Michael S. Khodadoust, Youn H. Kim, Christian M. Schürch, Garry P. Nolan
Format: article
Language:EN
Published: Nature Portfolio 2021
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Science
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Online Access:https://doaj.org/article/185b95b3ae0241efb2f75ef0ed8fba8c
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https://doaj.org/article/185b95b3ae0241efb2f75ef0ed8fba8c

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