Effect of small molecules modulating androgen receptor (SARMs) in human prostate cancer models.

Effect of small molecules modulating androgen receptor (SARMs) in human prostate cancer models.

The management of hormone-refractory prostate cancer represents a major challenge in the therapy of this tumor, and identification of novel androgen receptor antagonists is needed to render treatment more effective. We analyzed the activity of two novel androgen receptor antagonists, (S)-11 and (R)-...

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Autores principales: Anna Tesei, Carlo Leonetti, Marzia Di Donato, Elisa Gabucci, Manuela Porru, Greta Varchi, Andrea Guerrini, Dino Amadori, Chiara Arienti, Sara Pignatta, Giulia Paganelli, Michele Caraglia, Gabriella Castoria, Wainer Zoli
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1862085ca7bf4eeca8183e3e7658b889
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https://doaj.org/article/1862085ca7bf4eeca8183e3e7658b889

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