The MC4R p.Ile269Asn mutation confers a high risk for type 2 diabetes in the Mexican population via obesity dependent and independent effects

The MC4R p.Ile269Asn mutation confers a high risk for type 2 diabetes in the Mexican population via obesity dependent and independent effects

Abstract We investigated the association between the loss-of-function mutation MC4R p.Ile269Asn and T2D risk in the Mexican population. We enrolled 6929 adults [3175 T2D cases and 3754 normal glucose tolerant (NGT) controls] and 994 NGT children in the study. Anthropometric data and T2D-related quan...

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Autores principales: Miguel Vázquez-Moreno, Daniel Locia-Morales, Adan Valladares-Salgado, Tanmay Sharma, Aleyda Perez-Herrera, Roxana Gonzalez-Dzib, Francisco Rodríguez-Ruíz, Niels Wacher-Rodarte, Miguel Cruz, David Meyre
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1876f4c9831d41798d9cb65071b717a1
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https://doaj.org/article/1876f4c9831d41798d9cb65071b717a1

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