Antinociceptive and Antipruritic Effects of HSK21542, a Peripherally-Restricted Kappa Opioid Receptor Agonist, in Animal Models of Pain and Itch

Antinociceptive and Antipruritic Effects of HSK21542, a Peripherally-Restricted Kappa Opioid Receptor Agonist, in Animal Models of Pain and Itch

Kappa opioid receptor (KOR) agonists have been promising therapeutic candidates, owing to their potential for relieving pain and treating intractable pruritus. Although lacking morphine-like central nervous system (CNS) effects, KOR agonists do elicit sedation, dysphoria and diuresis which seriously...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Xin Wang, Xiaoli Gou, Xiaojuan Yu, Dongdong Bai, Bowei Tan, Pingfeng Cao, Meilin Qian, Xiaoxiao Zheng, Hairong Wang, Pingming Tang, Chen Zhang, Fei Ye, Jia Ni
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
HSK21542
kappa opioid receptor
pain
pruritus
animal models
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/1887529fd32b4df59dbadda726d129cb
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/1887529fd32b4df59dbadda726d129cb

Ejemplares similares