Premature differentiation of nephron progenitor cell and dysregulation of gene pathways critical to kidney development in a model of preterm birth

Abstract Preterm birth is a leading cause of neonatal morbidity. Survivors have a greater risk for kidney dysfunction and hypertension. Little is known about the molecular changes that occur in the kidney of individuals born preterm. Here, we demonstrate that mice delivered two days prior to full te...

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Auteurs principaux: Aleksandra Cwiek, Masako Suzuki, Kimberly deRonde, Mark Conaway, Kevin M. Bennett, Samir El Dahr, Kimberly J. Reidy, Jennifer R. Charlton
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/18b43f87c303431d9d6ae315e4174c3d
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