KCa3.1 channel blockade attenuates microvascular remodelling in a large animal model of bleomycin-induced pulmonary fibrosis

Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with limited therapeutic options and poor prognosis. IPF has been associated with aberrant vascular remodelling, however the role of vascular remodelling in pulmonary fibrosis is poorly understood. Here, we used a nov...

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Autores principales: Habtamu B. Derseh, Sasika N. Vithana Dewage, Kopiyawaththage U. E. Perera, Charles N. Pagel, Emmanuel Koumoundouros, Louise Organ, Ken J. Snibson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/18bd2ab7a74e400796b59f1eeaf6c5b4
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