Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples.
The quality of tissue samples and extracted mRNA is a major source of variability in tumor transcriptome analysis using genome-wide expression microarrays. During and immediately after surgical tumor resection, tissues are exposed to metabolic, biochemical and physical stresses characterized as &quo...
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Main Authors: | Elodie Caboux, Maria Paciencia, Geoffroy Durand, Nivonirina Robinot, Magdalena B Wozniak, Françoise Galateau-Salle, Graham Byrnes, Pierre Hainaut, Florence Le Calvez-Kelm |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/18e496b5f0484fe89c3f3e7a112acbed |
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