Glycan-mediated enhancement of reovirus receptor binding

The reovirus outercapsid protein σ1 binds to α-linked sialic acid and junctional adhesion molecule A (JAM-A) for virus entry. Here, combining atomic force microscopy and confocal microscopy, the authors provide insights into the dynamics of these interactions at the single-virion level in living cel...

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Autores principales: Melanie Koehler, Pavithra Aravamudhan, Camila Guzman-Cardozo, Andra C. Dumitru, Jinsung Yang, Serena Gargiulo, Patrice Soumillion, Terence S. Dermody, David Alsteens
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/18f1c9f75cb84361a7d2dc3c6a719136
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