Glycan-mediated enhancement of reovirus receptor binding

The reovirus outercapsid protein σ1 binds to α-linked sialic acid and junctional adhesion molecule A (JAM-A) for virus entry. Here, combining atomic force microscopy and confocal microscopy, the authors provide insights into the dynamics of these interactions at the single-virion level in living cel...

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Autores principales:	Melanie Koehler, Pavithra Aravamudhan, Camila Guzman-Cardozo, Andra C. Dumitru, Jinsung Yang, Serena Gargiulo, Patrice Soumillion, Terence S. Dermody, David Alsteens
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/18f1c9f75cb84361a7d2dc3c6a719136
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spelling	oai:doaj.org-article:18f1c9f75cb84361a7d2dc3c6a7191362021-12-02T17:02:10ZGlycan-mediated enhancement of reovirus receptor binding10.1038/s41467-019-12411-22041-1723https://doaj.org/article/18f1c9f75cb84361a7d2dc3c6a7191362019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12411-2https://doaj.org/toc/2041-1723The reovirus outercapsid protein σ1 binds to α-linked sialic acid and junctional adhesion molecule A (JAM-A) for virus entry. Here, combining atomic force microscopy and confocal microscopy, the authors provide insights into the dynamics of these interactions at the single-virion level in living cells.Melanie KoehlerPavithra AravamudhanCamila Guzman-CardozoAndra C. DumitruJinsung YangSerena GargiuloPatrice SoumillionTerence S. DermodyDavid AlsteensNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Melanie Koehler Pavithra Aravamudhan Camila Guzman-Cardozo Andra C. Dumitru Jinsung Yang Serena Gargiulo Patrice Soumillion Terence S. Dermody David Alsteens Glycan-mediated enhancement of reovirus receptor binding
description	The reovirus outercapsid protein σ1 binds to α-linked sialic acid and junctional adhesion molecule A (JAM-A) for virus entry. Here, combining atomic force microscopy and confocal microscopy, the authors provide insights into the dynamics of these interactions at the single-virion level in living cells.
format	article
author	Melanie Koehler Pavithra Aravamudhan Camila Guzman-Cardozo Andra C. Dumitru Jinsung Yang Serena Gargiulo Patrice Soumillion Terence S. Dermody David Alsteens
author_facet	Melanie Koehler Pavithra Aravamudhan Camila Guzman-Cardozo Andra C. Dumitru Jinsung Yang Serena Gargiulo Patrice Soumillion Terence S. Dermody David Alsteens
author_sort	Melanie Koehler
title	Glycan-mediated enhancement of reovirus receptor binding
title_short	Glycan-mediated enhancement of reovirus receptor binding
title_full	Glycan-mediated enhancement of reovirus receptor binding
title_fullStr	Glycan-mediated enhancement of reovirus receptor binding
title_full_unstemmed	Glycan-mediated enhancement of reovirus receptor binding
title_sort	glycan-mediated enhancement of reovirus receptor binding
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/18f1c9f75cb84361a7d2dc3c6a719136
work_keys_str_mv	AT melaniekoehler glycanmediatedenhancementofreovirusreceptorbinding AT pavithraaravamudhan glycanmediatedenhancementofreovirusreceptorbinding AT camilaguzmancardozo glycanmediatedenhancementofreovirusreceptorbinding AT andracdumitru glycanmediatedenhancementofreovirusreceptorbinding AT jinsungyang glycanmediatedenhancementofreovirusreceptorbinding AT serenagargiulo glycanmediatedenhancementofreovirusreceptorbinding AT patricesoumillion glycanmediatedenhancementofreovirusreceptorbinding AT terencesdermody glycanmediatedenhancementofreovirusreceptorbinding AT davidalsteens glycanmediatedenhancementofreovirusreceptorbinding
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Glycan-mediated enhancement of reovirus receptor binding

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