The immunoreceptor NKG2D promotes tumour growth in a model of hepatocellular carcinoma

Expression of NKG2D immunoreceptor ligands on tumour cells is believed to inhibit tumour growth through engaging NKG2D-expressing immune cells. Here, the authors show that in a model of liver cancer the NKG2D/NKG2D-ligand pathway can also promote tumour formation by sustaining an inflammatory enviro...

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Auteurs principaux: Sam Sheppard, Joana Guedes, Anna Mroz, Anastasia-Maria Zavitsanou, Hiromi Kudo, Stephen M. Rothery, Panagiotis Angelopoulos, Robert Goldin, Nadia Guerra
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/19101936214342739334b5deafccc5f2
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