Identification of two major autoantigens negatively regulating endothelial activation in Takayasu arteritis
Autoantibodies against endothelium have been recognized in Takayasu arteritis (TAK). Here the authors identify endothelial protein C receptor and scavenger receptor class B type 1 as major autoantigens in TAK, and find autoantibodies inhibit the negative regulation of endothelial activation.
Saved in:
Main Authors: | Tomoyuki Mutoh, Tsuyoshi Shirai, Tomonori Ishii, Yuko Shirota, Fumiyoshi Fujishima, Fumiaki Takahashi, Yoichi Kakuta, Yoshitake Kanazawa, Atsushi Masamune, Yoshikatsu Saiki, Hideo Harigae, Hiroshi Fujii |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/192eadb852e54eccb4c6ea32d8f3dee2 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Intracranial Involvement in Takayasu’s Arteritis
by: Andrea Johnson, et al.
Published: (2021) -
Specific microbiome profile in Takayasu’s arteritis and giant cell arteritis
by: Anne Claire Desbois, et al.
Published: (2021) -
Takayasu Arteritis – A Systematic Review
by: Hrisrova D., et al.
Published: (2019) -
Takayasu arteritis: Prevalence and clinical presentation in Switzerland.
by: Andrea D Gloor, et al.
Published: (2021) -
Hypoperfusive and hypertensive ocular manifestations in Takayasu arteritis
by: Jayanthi Peter, et al.
Published: (2010)