Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas

Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas

Gliomas are tumors often associated with epigenetics-related gene deregulation. Here the authors reveal an atlas of active enhancers and promoters in benign and malignant gliomas by performing whole-genome mapping of chromatin accessibility, histone modifications, DNA methylation patterns and transc...

Full description

Saved in:
Bibliographic Details
Main Authors: Karolina Stępniak, Magdalena A. Machnicka, Jakub Mieczkowski, Anna Macioszek, Bartosz Wojtaś, Bartłomiej Gielniewski, Katarzyna Poleszak, Malgorzata Perycz, Sylwia K. Król, Rafał Guzik, Michał J. Dąbrowski, Michał Dramiński, Marta Jardanowska, Ilona Grabowicz, Agata Dziedzic, Hanna Kranas, Karolina Sienkiewicz, Klev Diamanti, Katarzyna Kotulska, Wiesława Grajkowska, Marcin Roszkowski, Tomasz Czernicki, Andrzej Marchel, Jan Komorowski, Bozena Kaminska, Bartek Wilczyński
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/19342f80dced49aba9a14fb218e8e058
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/19342f80dced49aba9a14fb218e8e058

Similar Items