TRAF3 enhances TCR signaling by regulating the inhibitors Csk and PTPN22
Abstract The adaptor protein TNF receptor associated factor (TRAF) 3 is required for effective TCR signaling and normal T cell effector functions, and associates with the CD3/CD28 complex upon activation. To determine how TRAF3 promotes proximal TCR signaling, we studied TRAF3-deficient mouse and hu...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2017
|
| Subjects: | |
| Online Access: | https://doaj.org/article/193ddd2d1b1a4ac4ac05b3cd822eef66 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|