Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci

Genomic polymorphisms affect the epigenome, which in turn influences how epigenome- and genome-wide analysis are interpreted. Here, the authors characterise allelic differences in DNA methylation driven by obligatory or facilitative genetic effects, which may affect disease-related loci.

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Bibliographic Details
Main Authors: Christopher G. Bell, Fei Gao, Wei Yuan, Leonie Roos, Richard J. Acton, Yudong Xia, Jordana Bell, Kirsten Ward, Massimo Mangino, Pirro G. Hysi, Jun Wang, Timothy D. Spector
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/193f30fb3ee44bea8996117919657ad9
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