Analysis of cancer genomes reveals basic features of human aging and its role in cancer development

Somatic mutations are associated with disease, including cancer. Here, the authors analyse cancer genomic data and show that somatic mutations increase with age and that cancer incidence lags 15 years behind this increase, later in life, mutation and cancer incidence are reduced.

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Autores principales: Dmitriy I. Podolskiy, Alexei V. Lobanov, Gregory V. Kryukov, Vadim N. Gladyshev
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/194930feb5f74d6d8e7f05ca0400f466
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