Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut

Zinc is an essential cofactor for bacterial metabolism. Here, the authors show that the probiotic bacterium Escherichia coli Nissle 1917 utilizes the siderophore yersiniabactin as a zincophore, allowing the microbe to grow in zinc-limited media and to thrive in the inflamed gut.

Guardado en:

Detalles Bibliográficos
Autores principales:	Judith Behnsen, Hui Zhi, Allegra T. Aron, Vivekanandan Subramanian, William Santus, Michael H. Lee, Romana R. Gerner, Daniel Petras, Janet Z. Liu, Keith D. Green, Sarah L. Price, Jose Camacho, Hannah Hillman, Joshua Tjokrosurjo, Nicola P. Montaldo, Evelyn M. Hoover, Sean Treacy-Abarca, Benjamin A. Gilston, Eric P. Skaar, Walter J. Chazin, Sylvie Garneau-Tsodikova, Matthew B. Lawrenz, Robert D. Perry, Sean-Paul Nuccio, Pieter C. Dorrestein, Manuela Raffatellu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/19617c74d04844b3a0b478ff2c84a9cf
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:19617c74d04844b3a0b478ff2c84a9cf
record_format	dspace
spelling	oai:doaj.org-article:19617c74d04844b3a0b478ff2c84a9cf2021-12-05T12:22:26ZSiderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut10.1038/s41467-021-27297-22041-1723https://doaj.org/article/19617c74d04844b3a0b478ff2c84a9cf2021-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27297-2https://doaj.org/toc/2041-1723Zinc is an essential cofactor for bacterial metabolism. Here, the authors show that the probiotic bacterium Escherichia coli Nissle 1917 utilizes the siderophore yersiniabactin as a zincophore, allowing the microbe to grow in zinc-limited media and to thrive in the inflamed gut.Judith BehnsenHui ZhiAllegra T. AronVivekanandan SubramanianWilliam SantusMichael H. LeeRomana R. GernerDaniel PetrasJanet Z. LiuKeith D. GreenSarah L. PriceJose CamachoHannah HillmanJoshua TjokrosurjoNicola P. MontaldoEvelyn M. HooverSean Treacy-AbarcaBenjamin A. GilstonEric P. SkaarWalter J. ChazinSylvie Garneau-TsodikovaMatthew B. LawrenzRobert D. PerrySean-Paul NuccioPieter C. DorresteinManuela RaffatelluNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Judith Behnsen Hui Zhi Allegra T. Aron Vivekanandan Subramanian William Santus Michael H. Lee Romana R. Gerner Daniel Petras Janet Z. Liu Keith D. Green Sarah L. Price Jose Camacho Hannah Hillman Joshua Tjokrosurjo Nicola P. Montaldo Evelyn M. Hoover Sean Treacy-Abarca Benjamin A. Gilston Eric P. Skaar Walter J. Chazin Sylvie Garneau-Tsodikova Matthew B. Lawrenz Robert D. Perry Sean-Paul Nuccio Pieter C. Dorrestein Manuela Raffatellu Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut
description	Zinc is an essential cofactor for bacterial metabolism. Here, the authors show that the probiotic bacterium Escherichia coli Nissle 1917 utilizes the siderophore yersiniabactin as a zincophore, allowing the microbe to grow in zinc-limited media and to thrive in the inflamed gut.
format	article
author	Judith Behnsen Hui Zhi Allegra T. Aron Vivekanandan Subramanian William Santus Michael H. Lee Romana R. Gerner Daniel Petras Janet Z. Liu Keith D. Green Sarah L. Price Jose Camacho Hannah Hillman Joshua Tjokrosurjo Nicola P. Montaldo Evelyn M. Hoover Sean Treacy-Abarca Benjamin A. Gilston Eric P. Skaar Walter J. Chazin Sylvie Garneau-Tsodikova Matthew B. Lawrenz Robert D. Perry Sean-Paul Nuccio Pieter C. Dorrestein Manuela Raffatellu
author_facet	Judith Behnsen Hui Zhi Allegra T. Aron Vivekanandan Subramanian William Santus Michael H. Lee Romana R. Gerner Daniel Petras Janet Z. Liu Keith D. Green Sarah L. Price Jose Camacho Hannah Hillman Joshua Tjokrosurjo Nicola P. Montaldo Evelyn M. Hoover Sean Treacy-Abarca Benjamin A. Gilston Eric P. Skaar Walter J. Chazin Sylvie Garneau-Tsodikova Matthew B. Lawrenz Robert D. Perry Sean-Paul Nuccio Pieter C. Dorrestein Manuela Raffatellu
author_sort	Judith Behnsen
title	Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut
title_short	Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut
title_full	Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut
title_fullStr	Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut
title_full_unstemmed	Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut
title_sort	siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/19617c74d04844b3a0b478ff2c84a9cf
work_keys_str_mv	AT judithbehnsen siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT huizhi siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT allegrataron siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT vivekanandansubramanian siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT williamsantus siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT michaelhlee siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT romanargerner siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT danielpetras siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT janetzliu siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT keithdgreen siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT sarahlprice siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT josecamacho siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT hannahhillman siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT joshuatjokrosurjo siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT nicolapmontaldo siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT evelynmhoover siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT seantreacyabarca siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT benjaminagilston siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT ericpskaar siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT walterjchazin siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT sylviegarneautsodikova siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT matthewblawrenz siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT robertdperry siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT seanpaulnuccio siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT pietercdorrestein siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut AT manuelaraffatellu siderophoremediatedzincacquisitionenhancesenterobacterialcolonizationoftheinflamedgut
_version_	1718372002352332800

Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut

Ejemplares similares