Structure and functional implications of WYL domain-containing bacterial DNA damage response regulator PafBC

The transcriptional activator PafBC is a regulator of mycobacterial DNA damage response and upregulates genes involved in DNA repair. Here, the authors present the crystal structure of Arthrobacter aurescens PafBC and suggest that PafBC might be activated by binding of a nucleic acid ligand, and bio...

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Autores principales: Andreas U. Müller, Marc Leibundgut, Nenad Ban, Eilika Weber-Ban
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/196f288ac0fa4087a69e6983316b3dcd
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