Cyclophosphamide Attenuates Fibrosis in Lupus Nephritis by Regulating Mesangial Cell Cycle Progression

Objectives. Most patients with systemic lupus erythematosus (SLE) develop lupus nephritis (LN) with severe kidney manifestations. Renal fibrosis can be primarily attributed to overproliferation of mesangial cells (MCs), which are subject to drug treatment. Nevertheless, the detailed mechanisms remai...

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Auteurs principaux: Yuehong Ma, Ling Fang, Rui Zhang, Peng Zhao, Yafeng Li, Rongshan Li
Format: article
Langue:EN
Publié: Hindawi Limited 2021
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Accès en ligne:https://doaj.org/article/198043f3fa6f44c687756c69e42edfd3
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