Cyclophosphamide Attenuates Fibrosis in Lupus Nephritis by Regulating Mesangial Cell Cycle Progression

Objectives. Most patients with systemic lupus erythematosus (SLE) develop lupus nephritis (LN) with severe kidney manifestations. Renal fibrosis can be primarily attributed to overproliferation of mesangial cells (MCs), which are subject to drug treatment. Nevertheless, the detailed mechanisms remai...

Full description

Saved in:
Bibliographic Details
Main Authors: Yuehong Ma, Ling Fang, Rui Zhang, Peng Zhao, Yafeng Li, Rongshan Li
Format: article
Language:EN
Published: Hindawi Limited 2021
Subjects:
Online Access:https://doaj.org/article/198043f3fa6f44c687756c69e42edfd3
Tags: Add Tag
No Tags, Be the first to tag this record!