Inhibition of indole production increases the activity of quinolone antibiotics against E. coli persisters
Abstract Persisters are a sub-population of genetically sensitive bacteria that survive antibiotic treatment by entering a dormant state. The emergence of persisters from dormancy after antibiotic withdrawal leads to recurrent infection. Indole is an aromatic molecule with diverse signalling roles,...
Guardado en:
Autores principales: | Ashraf Zarkan, Marta Matuszewska, Stephen B. Trigg, Meng Zhang, Daaniyah Belgami, Cameron Croft, Junyan Liu, Sawssen El-Ouisi, Jack Greenhalgh, James S. Duboff, Taufiq Rahman, David K. Summers |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/199fed1a3da64621a877189cfbb04dfd |
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