Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals

Embryonic development produces different cell types in response to a small number of inductive signals. Here, the authors characterise how maternal factors modify chromatin to specify initial competence in Xenopus tropicalis, finding that the pioneering activity of the pluripotency factors Pou5f3 an...

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Autores principales: George E. Gentsch, Thomas Spruce, Nick D. L. Owens, James C. Smith
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/19a7d45a59f441d6bd501e207aa0ea14
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