Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals

Embryonic development produces different cell types in response to a small number of inductive signals. Here, the authors characterise how maternal factors modify chromatin to specify initial competence in Xenopus tropicalis, finding that the pioneering activity of the pluripotency factors Pou5f3 an...

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Auteurs principaux: George E. Gentsch, Thomas Spruce, Nick D. L. Owens, James C. Smith
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/19a7d45a59f441d6bd501e207aa0ea14
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