Solution structure and interaction with copper in vitro and in living cells of the first BIR domain of XIAP

Abstract The X-chromosome linked inhibitor of apoptosis (XIAP) is a multidomain metalloprotein involved in caspase inhibition and in copper homeostasis. It contains three zinc-binding baculoviral IAP repeats (BIR) domains, which are responsible for caspase interaction. Recently, it has been suggeste...

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Main Authors: Meng-Meng Hou, Panagis Polykretis, Enrico Luchinat, Xiao Wang, Shen-Na Chen, Hui-Hui Zuo, Yin Yang, Jia-Liang Chen, Yansheng Ye, Conggang Li, Lucia Banci, Xun-Cheng Su
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/19a844c194a644ec9b6abc7de73a76ed
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