Preventive CCL2/CCR2 Axis Blockade Suppresses Osteoclast Activity in a Mouse Model of Rheumatoid Arthritis by Reducing Homing of CCR2hi Osteoclast Progenitors to the Affected Bone
Detailed characterization of medullary and extramedullary reservoirs of osteoclast progenitors (OCPs) is required to understand the pathophysiology of increased periarticular and systemic bone resorption in arthritis. In this study, we focused on identifying the OCP population specifically induced b...
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Autores principales: | , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/19b1ea8888ac4196b38ea6e603c61165 |
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