Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies

Differential expression (DE) and gene set enrichment (GSE) analysis tend to be carried out separately. Here, the authors present iDEA (integrative Differential expression and gene set Enrichment Analysis) for the analysis of scRNAseq data which uses a Baysian approach to jointly model DE and GSE for...

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Autores principales: Ying Ma, Shiquan Sun, Xuequn Shang, Evan T. Keller, Mengjie Chen, Xiang Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/19d63e4d079b409da993da1c785284aa
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