Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies

Differential expression (DE) and gene set enrichment (GSE) analysis tend to be carried out separately. Here, the authors present iDEA (integrative Differential expression and gene set Enrichment Analysis) for the analysis of scRNAseq data which uses a Baysian approach to jointly model DE and GSE for...

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Bibliographic Details
Main Authors: Ying Ma, Shiquan Sun, Xuequn Shang, Evan T. Keller, Mengjie Chen, Xiang Zhou
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
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Online Access:https://doaj.org/article/19d63e4d079b409da993da1c785284aa
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