Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies
Differential expression (DE) and gene set enrichment (GSE) analysis tend to be carried out separately. Here, the authors present iDEA (integrative Differential expression and gene set Enrichment Analysis) for the analysis of scRNAseq data which uses a Baysian approach to jointly model DE and GSE for...
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Auteurs principaux: | Ying Ma, Shiquan Sun, Xuequn Shang, Evan T. Keller, Mengjie Chen, Xiang Zhou |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/19d63e4d079b409da993da1c785284aa |
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