De novo polymerase activity and oligomerization of hepatitis C virus RNA-dependent RNA-polymerases from genotypes 1 to 5.
Hepatitis C virus (HCV) shows a great geographical diversity reflected in the high number of circulating genotypes and subtypes. The response to HCV treatment is genotype specific, with the predominant genotype 1 showing the lowest rate of sustained virological response. Virally encoded enzymes are...
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Auteurs principaux: | , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/19ddb3067d4245359f3c0dc954995d8e |
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