Pertuzumab Cardiotoxicity in Patients With HER2-Positive Cancer: A Systematic Review and Meta-analysis

Pertuzumab Cardiotoxicity in Patients With HER2-Positive Cancer: A Systematic Review and Meta-analysis

Background: Human epidermal growth factor receptor 2 (HER2) overexpressing malignancies, including breast and gastro-esophageal, are associated with a poor prognosis. The cardiotoxicity of trastuzumab, a HER2-targeting monoclonal antibody, is well established. However, the cardiotoxic effect of pert...

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Main Authors: Muhammad Mustafa Alhussein, MD, Abir Mokbel, MD, MSc, Tammy Cosman, RN(EC), PhD, Nazanin Aghel, MD, Eric H. Yang, MD, Som D. Mukherjee, MD, Susan Dent, MD, Peter M. Ellis, MBBS, MMed, PhD, Sukhbinder Dhesy-Thind, MD, MSc, Darryl P. Leong, MBBS, MPH, M. Biostat, PhD
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Diseases of the circulatory (Cardiovascular) system
RC666-701
Online Access:https://doaj.org/article/19ebfb6c8fb04bf8886b70411a949d57
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https://doaj.org/article/19ebfb6c8fb04bf8886b70411a949d57

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