20S immunoproteasomes remove formaldehyde-damaged cytoplasmic proteins suppressing caspase-independent cell death

Abstract Immunoproteasomes are known for their involvement in antigen presentation. However, their broad tissue presence and other evidence are indicative of nonimmune functions. We examined a role for immunoproteasomes in cellular responses to the endogenous and environmental carcinogen formaldehyd...

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Autores principales: Sara Ortega-Atienza, Casey Krawic, Lauren Watts, Caitlin McCarthy, Michal W. Luczak, Anatoly Zhitkovich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/19f101b59bc04e38be53c554606594ca
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