Lipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factor-kappa B.
Inflammation and oxidative stress have been implicated in the pathophysiology of Parkinson's disease (PD) and inhibition of microglial activation attenuates degeneration of dopaminergic (DA) neurons in animal models of PD. Loss-of-function mutations in the parkin gene, which encodes an E3 ubiqu...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2011
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/19fbc2bad9e34893bfeb3afba3b13690 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|