Modulation of α-enolase post-translational modifications by dengue virus: increased secretion of the basic isoforms in infected hepatic cells.

Hepatic cells are major sites of dengue virus (DENV) replication and liver injury constitutes a characteristic of severe forms of dengue. The role of hepatic cells in dengue pathogenesis is not well established, but since hepatocytes are the major source of plasma proteins, changes in protein secret...

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Autores principales: Luiza M Higa, Bruno M Curi, Renato S Aguiar, Cynthia C Cardoso, André G De Lorenzi, Silvia L F Sena, Russolina B Zingali, Andrea T Da Poian
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/19ff55291d9b4b639ab4f299a195e64c
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