Ultra-sensitive digital quantification of proteins and mRNA in single cells

Digital proximity ligation assay (dPLA) can measure proteins and mRNAs in single cells, but is not compatible with cell imaging and cannot quantify rare proteins due to a high dilution factor. Here the authors present an automated microfluidic device that combines live-cell imaging, chemical stimula...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jing Lin, Christian Jordi, Minjun Son, Hoang Van Phan, Nir Drayman, Mustafa Fatih Abasiyanik, Luke Vistain, Hsiung-Lin Tu, Savaş Tay
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/1a00989204844592904106524e044438
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!