Mechanism of FGF receptor dimerization and activation

Different fibroblast growth factor (fgf) ligands elicit specific biological responses, but the mechanism directing this specificity is unknown. Here the authors show that fgf1 and fgf2 impose specific reorganizations on the fgf receptor dimer trans-membrane helices that result in distinct level of r...

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Bibliographic Details
Main Authors: Sarvenaz Sarabipour, Kalina Hristova
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/1a38664e03e44270bc0b16309c7d2525
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