Mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation

Digital information can be stored in monomer sequences of non-natural macromolecules, but only short chains can be read. Here the authors show long multi-byte digital polymers sequenced in a moderate resolution mass spectrometer. Full sequence coverage can be attained without pre-analysis digestion...

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Autores principales: Abdelaziz Al Ouahabi, Jean-Arthur Amalian, Laurence Charles, Jean-François Lutz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/1a3acb511c944ad18d104231bd9b0efe
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