Mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation

Digital information can be stored in monomer sequences of non-natural macromolecules, but only short chains can be read. Here the authors show long multi-byte digital polymers sequenced in a moderate resolution mass spectrometer. Full sequence coverage can be attained without pre-analysis digestion...

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Autores principales:	Abdelaziz Al Ouahabi, Jean-Arthur Amalian, Laurence Charles, Jean-François Lutz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1a3acb511c944ad18d104231bd9b0efe
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spelling	oai:doaj.org-article:1a3acb511c944ad18d104231bd9b0efe2021-12-02T17:06:27ZMass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation10.1038/s41467-017-01104-32041-1723https://doaj.org/article/1a3acb511c944ad18d104231bd9b0efe2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01104-3https://doaj.org/toc/2041-1723Digital information can be stored in monomer sequences of non-natural macromolecules, but only short chains can be read. Here the authors show long multi-byte digital polymers sequenced in a moderate resolution mass spectrometer. Full sequence coverage can be attained without pre-analysis digestion or the help from sequence databases.Abdelaziz Al OuahabiJean-Arthur AmalianLaurence CharlesJean-François LutzNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Abdelaziz Al Ouahabi Jean-Arthur Amalian Laurence Charles Jean-François Lutz Mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation
description	Digital information can be stored in monomer sequences of non-natural macromolecules, but only short chains can be read. Here the authors show long multi-byte digital polymers sequenced in a moderate resolution mass spectrometer. Full sequence coverage can be attained without pre-analysis digestion or the help from sequence databases.
format	article
author	Abdelaziz Al Ouahabi Jean-Arthur Amalian Laurence Charles Jean-François Lutz
author_facet	Abdelaziz Al Ouahabi Jean-Arthur Amalian Laurence Charles Jean-François Lutz
author_sort	Abdelaziz Al Ouahabi
title	Mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation
title_short	Mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation
title_full	Mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation
title_fullStr	Mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation
title_full_unstemmed	Mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation
title_sort	mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1a3acb511c944ad18d104231bd9b0efe
work_keys_str_mv	AT abdelazizalouahabi massspectrometrysequencingoflongdigitalpolymersfacilitatedbyprogrammedinterbytefragmentation AT jeanarthuramalian massspectrometrysequencingoflongdigitalpolymersfacilitatedbyprogrammedinterbytefragmentation AT laurencecharles massspectrometrysequencingoflongdigitalpolymersfacilitatedbyprogrammedinterbytefragmentation AT jeanfrancoislutz massspectrometrysequencingoflongdigitalpolymersfacilitatedbyprogrammedinterbytefragmentation
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Mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation

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